Particulate matter (PM) is a main component of air pollution, and can affect heart health. The EPA is continually taking steps to develop an approach to rapidly assess the cardiotoxicity potential of PM from different sources, and are calling the approach “Pathfinder Innovation Project (PIP)”. Many innovative approaches have been developed, including the use of Zebrafish as an analog to human cardiovascular health at various levels of exposure to PM from different sources. “The PIP program is an internal competition for EPA scientists to receive time to explore their biggest ideas in environmental research. The goal of this work is to identify PM sources and PM components that cause cardiovascular effects on a larger scale to expedite risk determinations associated with exposure to different air sheds.”
To read the full article from the EPA and how they used zebrafish to assess cardiotoxicity, click here.
Source: Pathfinder Innovation Project—Using Zebrafish to Quickly Screen Air Pollution Sources for Potential Impact on Heart Health, Aimen Farraj, https://blog.epa.gov/blog/2016/11/pathfinder-innovation-project-2/
Image Source: https://www.flickr.com/photos/nichd/20092260041